The web application you are attempting to access on this web server is currently unavailable

出错信息为:
Server Application Unavailable
The web application you are attempting to access on this web server is currently unavailable. Please hit the "Refresh" button in your web browser to retry your request.

Administrator Note: An error message detailing the cause of this specific request failure can be found in the system event log of the web server. Please review this log entry to discover what caused this error to occur.

在system event里查看错误：
aspnet_wp.exe (PID: 3068) stopped unexpectedly.

重装.Net FrameWork后问题依旧

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看错误信息好像说的是调试进程莫名中断，
你重起一下吧
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检查一下最后安装了什么软件，或做了什么操作，CTRL+Z应该就没有问题了！
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重新注册一下asp.net试试